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Talc pleurodesis UpToDate
网页2021年7月8日Talc pleurodesis is a specific form of chemical pleurodesis. Talc is the most effective sclerosant available for pleurodesis in malignant pleural effusion . As compared to indwelling pleural catheter placement, talc pleurodesis has been shown to be equally
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talc powder, sterile (Rx) Medscape DrugsDiseases
网页Powder: 5 g as single dose dispersed in sodium chloride injection 50 to 100 mL; doses range from 2 to 10.5 g shown to be effective Next: Adverse Effects Frequency Not
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Talc Pleurodesis for the Treatment of Pneumothorax and
网页Talc is a highly effective pleurodesis agent when administered either via poudrage or slurry in patients with pleural effusion or pneumothorax. Success rates are similar for
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Talc pleurodesis in malignant pleural effusion: a
网页2020年11月22日Although talc pleurodesis is widely used for managing malignant pleural effusions, there is still controversy in the literature regarding its superiority compared to
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Malignant pleural effusions and the role of talc poudrage
网页2014年10月27日Background: Malignant Pleural Effusion (MPE) is common with advanced malignancy. Palliative care with minimal adverse events is the cornerstone of
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Talc Wikipedia
网页Sterile talc powder ( NDC 63256-200-05) is a sclerosing agent used in the procedure of pleurodesis. This can be helpful as a cancer treatment to prevent pleural effusions (an abnormal collection of fluid in the space
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Iodized talc pleurodesis for the treatment of pleural
网页A slurry containing 5 gm of talc and 3 gm of thymol iodide was instilled into the pleural space through the chest tube. Chest tubes were removed after complete reexpansion
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Talc pleurodesis: comparison of talc slurry instillation with
网页Patients and methods: From 2000 to 2005, two methods of talc pleurodesis were performed in 71 patients with symptomatic massive malignant pleural effusions: a) through the
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Approval
网页STERILE TALC POWDER FDA FINAL VERSION For Intrapleural Administration Only DESCRIPTION Sterile Talc Powder is a sclerosing agent intended for intrapleural
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Efficacy and Safety of Talc Pleurodesis for Malignant
网页Malignant pleural effusion (MPE) is a common complication of advanced malignancy with a poor prognosis. It’s estimated that MPE affects more than 150,000 people each
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The modern diagnosis and management of
网页2015年9月8日Pleural effusions are common, Data from a Cochrane meta-analysis suggest that sterile talc powder is the most effective pleurodesis agent,25 and its use has now been adopted as standard in
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Pleurodesis Wikipedia
网页Sterile talc powder, administered intrapleurally via a chest tube, is indicated as a sclerosing agent to decrease the recurrence of malignant pleural effusions in symptomatic patients. It is usually performed at the time of a diagnostic thoracoscopy.
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Povidone-iodine pleurodesis versus talc pleurodesis in
网页2015年5月1日Talc, tetracycline and bleomycin have been widely used for pleurodesis. Many studies have shown the effectiveness and safety of Povidone-iodine as an agent for pleurodesis with achieving very good results [ 3, 15 ]. Our study included 39 cases divided into two groups; group A had talc pleurodesis and group B had povidone-iodine
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Talc Monograph for Professionals Drugs
网页2022年5月20日Pleural Effusions Intrapleural Aerosol Usually 4–8 g (from 1–2 spray canisters) as a single dose. Spray canister delivers talc at a rate of approximately 1.2 g per second; dose of talc delivered depends on extent and duration of manual compression of actuator button on the canister.
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Talc pleurodesis in malignant pleural effusion: a
网页2020年11月22日Talc pleurodesis is an effective MPE management approach presenting borderline statistically significant superiority compared to control methods especially compared to bleomycin as well as when pleurodesis success is evaluated later than 1 month postoperatively. Introduction
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Talc Pleurodesis for the Treatment of Pneumothorax
网页Talc Pleurodesis for the Treatment of Pneumothorax and Pleural Effusion Key words pleurodesis poudrage slurry talc Early interest in the development of pleural symphysis resulted from the desire of surgeons to produce adhesions to facilitate lobectomy. Various agents were tried but were found to be of limited value.
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Malignant pleural effusions and the role of talc
网页2014年10月27日Malignant pleural effusions and the role of talc poudrage and talc slurry: a systematic review and meta-analysis There is no difference in success rates of pleurodesis based on patient centered outcomes between talc poudrage and talc slurry treatments. Respiratory complications are more common with talc poudrage via thoracoscopy.
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Life expectancy of patients with malignant pleural
网页2006年6月1日Under direct thoracoscopic vision, 5 g of asbestos-free talc powder was insufflated into the pleural cavity with a manual insufflator to achieve even distribution of talc. The estimated Kaplan–Meier survival curve and 95% CI for patients with malignant pleural effusions treated with VATS talc pleurodesis.
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Drug Shortage Detail: Sterile Talc
网页2022年3月18日Before sterile talc powder became commercially available, extemporaneous formulations of asbestos-free talc, USP, were used for pleural effusions.[3] Large containers of the commercial grade talc are available in 100 gram and 500 gram sizes and institutions repackaged and sterilized these products in 5 gram
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Iodized talc pleurodesis for the treatment of pleural
网页A slurry containing 5 gm of talc and 3 gm of thymol iodide was instilled into the pleural space through the chest tube. Chest tubes were removed after complete reexpansion and clearing of the effusions, usually in 3 to 5 days. The patients' ages ranged from 26 to 88 years (average 50 years). Eighteen patients had lung carcinoma, two had
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The modern diagnosis and management of
网页2015年9月8日Pleural effusions are common, Data from a Cochrane meta-analysis suggest that sterile talc powder is the most effective pleurodesis agent,25 and its use has now been adopted as standard in
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Pleurodesis Wikipedia
网页Sterile talc powder, administered intrapleurally via a chest tube, is indicated as a sclerosing agent to decrease the recurrence of malignant pleural effusions in symptomatic patients. It is usually performed at the time of a diagnostic thoracoscopy.
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A mechanism for improved talc pleurodesis via foam
网页Abstract. Talcum powder is recognized as the leading drug for pleurodesis, a treatment of choice for malignant pleural effusions. Recently, it was shown that hydrogel foam delivery systems significantly enhanced the number of adhesions between the chest wall and the lung in a New Zealand rabbit model due to the sol-gel transition.
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Malignant pleural effusions and the role of talc
网页2014年10月27日Malignant pleural effusions and the role of talc poudrage and talc slurry: a systematic review and meta-analysis There is no difference in success rates of pleurodesis based on patient centered outcomes between talc poudrage and talc slurry treatments. Respiratory complications are more common with talc poudrage via thoracoscopy.
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Talc powder characterization for therapeutic particle
网页2006年1月1日The administration of talc particles to the pleural space for the treatment of pleural effusions has been practiced for nearly a century with little understanding of the key particle parameters
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Talcum Powder and Cancer American Cancer Society
网页When talking about whether talcum powder is linked to cancer, it is important to distinguish between talc that contains asbestos and talc that is asbestos-free. Talc that has asbestos is generally accepted as being able to cause cancer if it is inhaled. The evidence about asbestos-free talc is less clear. Researchers use 2 main types of studies
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Life expectancy of patients with malignant pleural
网页2006年6月1日Under direct thoracoscopic vision, 5 g of asbestos-free talc powder was insufflated into the pleural cavity with a manual insufflator to achieve even distribution of talc. The estimated Kaplan–Meier survival curve and 95% CI for patients with malignant pleural effusions treated with VATS talc pleurodesis.
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Drug Shortage Detail: Sterile Talc
网页2022年3月18日Talc is considered a highly effective pleurodesis agent. Alternative agents used for pleurodesis include bleomycin, doxycycline, iodine, and minocycline. [3,5-12] The decision on use of each agent will depend on the indication, availability of the products, and healthcare professional knowledge and preference. References
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Steritalc 4g (Novatech SA): FDA Package Insert
网页2023年1月12日Prepare the talc suspension using aseptic technique in an appropriate laminar flow hood as follows: Step 1: Fully bend or remove the flap into the direction of the arrow. The top can now be punctured to mix the slurry. Step 2: Using a 16 gauge needle attached to a 60-mL Luer Lok syringe, draw up 50 mL of 0.9 % Sodium Chloride
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Approval
网页In single-arm studies of malignant pleural effusions from the published literature, variously defined "success" rates using talc slurry pleurodesis ranged from 75% to 100%. INDICATIONS AND USAGE Sterile Talc Powder, administered intrapleurally via chest tube, is indicated as a sclerosing agent
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